JAK3 anticorps (pTyr980)

N° du produit ABIN8122384

Cet anticorps anti-JAK3 Polyclonal Lapin (ABIN8122384) détecte spécifiquement JAK3 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour JAK3 anticorps (pTyr980) (ABIN8122384)

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-JAK3 anticorps

Épitope: pTyr980

Fonction: Jak3 (Phospho Tyr980/981) Antibody

Specificité: This antibody detects endogenous levels of Human Mouse Jak3 (phospho-Tyr980 or 981)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized phosho peptide around human Jak3 (Tyr980 and 981)

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000,IHC 1:50-300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur JAK3

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Autre désignation: Jak3

Sujet:

Synonyms: Tyrosine-protein kinase JAK3 (EC 2.7.10.2) (Janus kinase 3) (JAK-3) (Leukocyte janus kinase) (L-JAK)

Background: The protein encoded byThis gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq, Jul 2008],

Gene Name: JAK3

Protein Name: Jak3 (Tyr980/981)

ID gène: 3718

UniProt: P52333

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response