PKC anticorps (AA 450-550)

N° du produit ABIN8124064

Cet anticorps anti-PKC Monoclonal Souris (Clone AB2366) (ABIN8124064) détecte spécifiquement PKC dans WB, IF et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Lapin.

Aperçu rapide pour PKC anticorps (AA 450-550) (ABIN8124064)

Antigène: PKC (Protein Kinase C (PKC))

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PKC est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), ELISA

Clone: AB2366

Détail du produit anti-PKC anticorps

Épitope: AA 450-550

Fonction: PKC mouse mAb

Specificité: This antibody detects endogenous levels of PKC protein.

Purification: The antibody was purified by protein G affinity chromatography.

Immunogène: A synthetic peptide corresponding to the amino acid region 450 - 550 of the human PKC protein.

Isotype: IgG

Information d'application

Indications d'application: WB, 1:500-1:2000 | IF, 1:100-1:500 | ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The antibody is provided in liquid form in phosphate - buffered saline with 50 % glycerol, 0.05 % BSA, and 0.05 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at-20°C. Avoid freeze / thaw cycles.

Détails sur PKC

Antigène: PKC (Protein Kinase C (PKC))

Autre désignation: PKC

Sujet:

Synonyms: Protein kinase C alpha type, PKC-A, PKC-alpha, PRKCA, PKCA, PRKACA, Protein kinase C beta type, PKC-B, PKC-beta, PRKCB, PKCB, PRKCB1, Protein kinase C gamma type, PKC-gamma, PRKCG, PKCG

Background: protein kinase C alpha (PRKCA) Homo sapiens Protein kinase C (PKC) is a family of serine-and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca (2+) handling in myocytes. [provided by RefSeq, Jul 2

Gene Name: PRKCA PRKCB PRKCG

Protein Name: PKC

ID gène: 5578

UniProt: P17252

Pathways: TCR Signaling, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Phototransduction