Retinoblastoma Binding Protein 8 anticorps (pSer327)

N° du produit ABIN8124334

Cet anticorps anti-Retinoblastoma Binding Protein 8 Polyclonal Lapin (ABIN8124334) détecte spécifiquement Retinoblastoma Binding Protein 8 dans ELISA et WB. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour Retinoblastoma Binding Protein 8 anticorps (pSer327) (ABIN8124334)

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: ELISA, Western Blotting (WB)

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Épitope: pSer327

Fonction: CTIP (Phospho Ser327) Antibody

Specificité: This antibody detects endogenous levels of Human,Mouse CTIP (Phospho Ser327)

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Immunogène: Synthesized peptide derived from human CTIP (Phospho Ser327)

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: CTIP

Sujet:

Synonyms: DNA endonuclease RBBP8 (EC 3.1.-.-, CtBP-interacting protein, CtIP, Retinoblastoma-binding protein 8, RBBP-8, Retinoblastoma-interacting protein and myosin-like, RIM, Sporulation in the absence of SPO11 protein 2 homolog, SAE2)

Background: The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq, Jul 2008],

Gene Name: RBBP8 CTIP

Protein Name: CTIP (Phospho Ser327)

ID gène: 5932

UniProt: Q99708

Pathways: Cycle Cellulaire, Réparation de l'ADN