SAG anticorps (AA 210-290)

N° du produit ABIN8124496

Cet anticorps anti-SAG Polyclonal Lapin (ABIN8124496) détecte spécifiquement SAG dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour SAG anticorps (AA 210-290) (ABIN8124496)

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAG est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-SAG anticorps

Épitope: AA 210-290

Fonction: ARRS Antibody

Specificité: ARRS Polyclonal Antibody detects endogenous levels of protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human protein . at AA range: 210-290

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000 ELISA 1:5000-20000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SAG

Antigène: SAG (S-Antigen, Retina and Pineal Gland (Arrestin) (SAG))

Autre désignation: ARRS

Sujet:

Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008],

Gene Name: SAG

Protein Name: S-arrestin (48 kDa protein) (Retinal S-antigen) (S-AG) (Rod photoreceptor arrestin)

ID gène: 6295

UniProt: P10523

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling