SQSTM1 anticorps

N° du produit ABIN8124591

L’anticorps anti-SQSTM1 Polyclonal Lapin est utilisé pour la détection de SQSTM1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IF.

Aperçu rapide pour SQSTM1 anticorps (ABIN8124591)

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SQSTM1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-SQSTM1 anticorps

Fonction: SQSTM1/p62 Antibody

Specificité: This antibody detects endogenous levels of SQSTM at Human/Mouse/Rat

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Synthesized peptide derived from human SQSTM

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000, IF ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C/1 year

Date de péremption: 12 months

Détails sur SQSTM1

Antigène: SQSTM1 (Sequestosome 1 (SQSTM1))

Autre désignation: SQSTM1/p62

Sujet:

Background: This gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa-B (NF-kB) signaling pathway. The protein functions as a scaffolding/adaptor protein in concert with TNF receptor-associated factor 6 to mediate activation of NF-kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in this gene result in sporadic and familial Paget disease of bone. [provided by RefSeq, Mar 2009],

Gene Name: SQSTM1 ORCA OSIL

Protein Name: SQSTM

ID gène: 8878

UniProt: Q13501

Pathways: Signalisation NF-kappaB, Neurotrophin Signaling Pathway, Autophagy