SMARCB1 anticorps (AA 301-385)

N° du produit ABIN762566

Détail du produit anti-SMARCB1 anticorps

Antigène: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Épitope: AA 301-385

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SMARCB1 est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris

Homologie: Rat,Cow,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SNF5

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SMARCB1 (ABIN762566)

McAndrew, Gjidoda, Tagore, Miksanek, Floer: "Chromatin Remodeler Recruitment during Macrophage Differentiation Facilitates Transcription Factor Binding to Enhancers in Mature Cells." dans: The Journal of biological chemistry, Vol. 291, Issue 35, pp. 18058-71, (2016) (PubMed).

Détails sur SMARCB1

Antigène: SMARCB1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 (SMARCB1))

Autre désignation: Snf5 (SMARCB1 Produits)

Synonymes: anticorps SMARCB1, anticorps BAF47, anticorps INI1, anticorps MRD15, anticorps RDT, anticorps RTPS1, anticorps SNF5, anticorps SNF5L1, anticorps Sfh1p, anticorps Snr1, anticorps hSNFS, anticorps AU020204, anticorps Baf47, anticorps Ini1, anticorps SNF5/INI1, anticorps Snf5, anticorps fc51b01, anticorps smarcb1, anticorps wu:fc51b01, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 S homeolog, anticorps SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1b, anticorps SMARCB1, anticorps Smarcb1, anticorps smarcb1.S, anticorps smarcb1b

Sujet:

Synonyms: Snr1, TYE4, BAF47, hSNF5, INI1 antibody Integrase interactor 1 protein, RDT, Sfh1p, SMARCB1, SNF5, SNF5L1, Snr1, Sucrose nonfermenting yeast homolog like 1, SWI/SNF complex component SNF5, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1, SWI10, Transcription factor TYE4, Transcription regulatory protein SNF5.

Background: SNF5 is involved in transcriptional activation. The SWI/SNF complex is required for the induced expression of a large number of genes. This complex alters chromatin structure to facilitate binding of gene-specific dedicated transcription factors. SNF5 also funtions as a tumor suppressor gene and is frequently mutated in malignant rhabdoid tumors. It is also involved in adipocyte differentiation.

ID gène: 6598

UniProt: Q12824