Nanog anticorps (AA 137-141)
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- Antigène Voir toutes Nanog (NANOG) Anticorps
- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Épitope
- AA 137-141
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Nanog est non-conjugé
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Application
- Western Blotting (WB)
- Séquence
- K-Q-V-K-T
- Specificité
- This antibody detects endogenous level of total Nanog protein.
- Réactivité croisée (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- Affinity Chromatography using epitope-specific peptide
- Immunogène
- Peptide sequence around aa.137~141 derived from Nanog
- Top Product
- Discover our top product NANOG Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % Sodium Azide and 50 % Glycerol
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -20 °C
- Stockage commentaire
- Store (in aliquots) at -20 °C.
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- Antigène
- Nanog (NANOG) (Nanog Homeobox (NANOG))
- Autre désignation
- NANOG (NANOG Produits)
- Synonymes
- anticorps 2410002E02Rik, anticorps ENK, anticorps ecat4, anticorps NANOG, anticorps hacp, anticorps wu:fd19e04, anticorps wu:fd20a07, anticorps zgc:193933, anticorps Nanog homeobox, anticorps nanog homeobox, anticorps Nanog, anticorps NANOG, anticorps nanog
- Sujet
- Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes By similarity. Acts as a transcriptional activator or repressor By similarity. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3' By similarity. When overexpressed, promotes cells to enter into S phase and proliferation.Synonyms: Homeobox protein NANOG
- Poids moléculaire
- 42 kDa
- ID gène
- 100293888
- NCBI Accession
- NP_079141
- UniProt
- Q9H9S0
- Pathways
- Stem Cell Maintenance
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