Retinoblastoma Binding Protein 8 anticorps (Center)

N° du produit ABIN783608

Détail du produit anti-Retinoblastoma Binding Protein 8 anticorps

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Épitope: Center

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Retinoblastoma Binding Protein 8 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Réactivité croisée (Details): Species reactivity (tested):Human, mouse, rat

Purification: Affinity chromatography purified via peptide column

Immunogène: 14 amino acid peptide near the center of human RBBP8

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur Retinoblastoma Binding Protein 8

Antigène: Retinoblastoma Binding Protein 8 (RBBP8)

Autre désignation: RBBP8 (RBBP8 Produits)

Synonymes: anticorps COM1, anticorps CTIP, anticorps JWDS, anticorps RIM, anticorps SAE2, anticorps SCKL2, anticorps 9930104E21Rik, anticorps CtIP, anticorps RBBP-8, anticorps RGD1308872, anticorps RBBP8, anticorps DKFZp469K0714, anticorps RB binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8, endonuclease, anticorps retinoblastoma binding protein 8 L homeolog, anticorps retinoblastoma binding protein 8, anticorps RBBP8, anticorps Rbbp8, anticorps rbbp8.L, anticorps rbbp8

Sujet: RBBP8, also known as CtBP (carboxy-terminal binding protein) interacting protein (CTIP), was characterized for its role in transcription as a cofactor for the transcriptional repressor CtBP, and also as a binding partner for other proteins including the cell cycle regulators retinoblastoma protein (Rb) and breast cancer 1 (BRCA1). It is ubiquitously expressed and localizes to the nucleus. RBBP8 is thought to modulate the functions in cell proliferation, transcriptional regulation and DNA repair. RBBP8 also plays a central role in the cell cycle checkpoint response to DNA double-stranded breaks (DSBs), with new evidence demonstrating that it controls the choice of DSB repair pathway.Synonyms: CTIP, CtBP-interacting protein, RBBP-8, Retinoblastoma-binding protein 8, Retinoblastoma-interacting protein and myosin-like

ID gène: 5932

NCBI Accession: NP_002885

UniProt: Q99708

Pathways: Cycle Cellulaire, Réparation de l'ADN