PPAPDC3 anticorps (N-Term)

N° du produit ABIN783832

Détail du produit anti-PPAPDC3 anticorps

Antigène: PPAPDC3 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 3 (PPAPDC3))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPAPDC3 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography

Immunogène: 19 amino acid peptide from near the amino of terminus human PPAPDC3.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at -20 °C.

Détails sur PPAPDC3

Antigène: PPAPDC3 (Phosphatidic Acid Phosphatase Type 2 Domain Containing 3 (PPAPDC3))

Autre désignation: PPAPDC3 (PPAPDC3 Produits)

Synonymes: anticorps MGC147268, anticorps im:7142624, anticorps zgc:77336, anticorps PPAPDC3, anticorps DKFZp468F176, anticorps C9orf67, anticorps NET39, anticorps D830019K17Rik, anticorps RGD1305821, anticorps phospholipid phosphatase 7 (inactive), anticorps phospholipid phosphatase 7, anticorps plpp7, anticorps PLPP7, anticorps Plpp7

Sujet: PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.Synonyms: C9orf67, Phosphatidic acid phosphatase type 2 domain-containing protein 3, Probable lipid phosphate phosphatase PPAPDC3

ID gène: 84814

NCBI Accession: NP_116117

UniProt: Q8NBV4

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development