TRAIL anticorps
Aperçu rapide pour TRAIL anticorps (ABIN783968)
Antigène
Voir toutes TRAIL (TNFSF10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes TRAIL.
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Réactivité croisée (Details)
- Species reactivity (tested):Mouse.
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Purification
- Affinity Chromatography employing an immobilized Murine TRAIL matrix
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Immunogène
- Highly pure recombinant Murine TRAIL.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Reconstitution
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS, pH 7.2 without preservatives
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
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Date de péremption
- 6 months
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- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
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Autre désignation
- CD253 / TRAIL
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Sujet
- TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic Death domain which activates the cell's apoptotic machinery.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
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ID gène
- 10850
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NCBI Accession
- NP_033451
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Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
Antigène
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