IDH3B anticorps (C-Term)

N° du produit ABIN784283

Détail du produit anti-IDH3B anticorps

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Épitope: AA 369-383, C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc, Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IDH3B est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-TTDFIKSVIG HLQTK

Specificité: This antibody is expected to recognize isoform a (NP_008830.2) and isoform c (NP_777281.1).

Réactivité croisée (Details): Species reactivity (expected):Human, Rat, Canine (Dog), Pig, Cow.
Species reactivity (tested):Mouse.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C Terminus of the protein sequence according to NP_008830.2, NP_777281.1. Genename: IDH3B

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur IDH3B

Antigène: IDH3B (Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B))

Autre désignation: Isocitric Dehydrogenase beta / IDH3B (IDH3B Produits)

Synonymes: anticorps H-IDHB, anticorps RP46, anticorps C78231, anticorps zgc:86647, anticorps MGC79028, anticorps IDH1, anticorps IDH3, anticorps isocitrate dehydrogenase 3 (NAD(+)) beta, anticorps isocitrate dehydrogenase 3 (NAD+) beta, anticorps isocitrate dehydrogenase 3 (NAD+) beta S homeolog, anticorps IDH3B, anticorps Idh3B, anticorps Idh3b, anticorps idh3b, anticorps idh3b.S

Sujet: Defects in IDH3B are the cause of retinitis pigmentosa type 46 (RP46) [MIM:612572]. RP is a retinal dystrophy belonging to the group of pigmentary retinopathies. RP is characterized by retinal pigment deposits visible on fundus examination and primary loss of rod photoreceptor cells followed by secondary loss of cone photoreceptors. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. Belongs to the isocitrate and isopropylmalate dehydrogenases family.Synonyms: NAD(+)-specific ICDH beta, mitochondrial Isocitrate dehydrogenase [NAD] subunit beta

ID gène: 3420

NCBI Accession: NP_008830