ATF2 anticorps

N° du produit ABIN865467

Cet anticorps anti-ATF2 Monoclonal Souris (Clone 4F12) (ABIN865467) détecte spécifiquement ATF2 dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour ATF2 anticorps (ABIN865467)

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATF2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 4F12

Détail du produit anti-ATF2 anticorps

Purification: Ascitic fluid

Immunogène: Purified recombinant fragment of human ATF2 expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application: WB: 1/500 - 1/2000, IHC: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100g/100l

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Détails sur ATF2

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Autre désignation: ATF2

Sujet: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. Tissue specificity: Abundant expression seen in the brain. Synonyms: HB16, CREB2, TREB7, CRE-BP1, MGC111558, ATF2

Poids moléculaire: 55kDa

ID gène: 1386

Pathways: Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades