IL10RA anticorps (Interleukin 10 Receptor, alpha) (pSer319)

Details for Product anti-IL10RA Antibody No. ABIN871407
Antigène
  • IL10R1
  • IL10RA
  • CD210
  • CD210a
  • CDW210A
  • HIL-10R
  • IL-10R1
  • IL10R
  • AW553859
  • CDw210
  • CDw210a
  • Il10r
  • mIL-10R
  • interleukin 10 receptor subunit alpha
  • interleukin 10 receptor, alpha
  • IL10RA
  • Il10ra
Épitope
pSer319
20
15
13
9
9
6
4
4
3
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivité
Humain
161
49
24
2
2
1
1
1
1
Hôte
Lapin
132
31
20
2
1
Clonalité
Polyclonal
Conjugué
Cet anticorp IL10RA est non-conjugé
13
9
6
4
4
4
4
4
4
4
2
2
1
1
1
1
1
Application
Western Blotting (WB)
111
55
36
27
24
13
12
6
6
5
3
2
1
1
Options
Immunogène Peptide sequence around phosphorylation site of pSer319, pSerine 323 (D-S (p) -G-F-G-S (p) -T) derived from Human IL-10R subunit alpha. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Specificité The antibody detects endogenous level of IL-10R subunit alpha protein only when phosphorylated at serine 319 and serine 323.
Purification Affinity purified
Plasmids, Primers & others Plasmids, Primers & others IL10RA products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation IL-10R subunit alpha (IL10RA Antibody Extrait)
Sujet Receptor for IL10, binds IL10 with a high affinity.
Poids moléculaire 63 kDa
ID gène 3587
NCBI Accession NP_001549
UniProt Q13651
Pathways Growth Factor Binding
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C/-20 °C
Stockage commentaire Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Produit citée dans: Jiang, Lu, Yuan, Liu: "Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase." dans: PLoS ONE, Vol. 6, Issue 11, pp. e27464, 2011 (PubMed).

Background publications Okwor, Liu, Beverley, Uzonna: "Inoculation of killed Leishmania major into immune mice rapidly disrupts immunity to a secondary challenge via IL-10-mediated process." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 33, pp. 13951-6, 2009 (PubMed).

Gonzalez, Burgaya, Acarin, Peluffo, Castellano, Gonzalez: "Interleukin-10 and interleukin-10 receptor-I are upregulated in glial cells after an excitotoxic injury to the postnatal rat brain." dans: Journal of neuropathology and experimental neurology, Vol. 68, Issue 4, pp. 391-403, 2009 (PubMed).

Chen, Liu, Wang, Wu, Feng, Zheng, Guo, Li, Wang, Cao: "Effects of CD4(+)CD25(+)Foxp3(+)regulatory T cells on early Plasmodium yoelii 17XL infection in BALB/c mice." dans: Parasitology, Vol. 136, Issue 10, pp. 1107-20, 2009 (PubMed).

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