HDAC8 anticorps (pSer39)

N° du produit ABIN871411

Détail du produit anti-HDAC8 anticorps

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Épitope: pSer39

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC8 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Specificité: The antibody detects endogenous level of HDAC8 only when phosphorylated at serine 39.

Purification: Affinity purified

Immunogène: Peptide sequence around phosphorylation site of pSer39 (R-A-S (p) -M-V) derived from Human HDAC8. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates.

Information d'application

Indications d'application: Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur HDAC8

Antigène: HDAC8 (Histone Deacetylase 8 (HDAC8))

Autre désignation: HDAC8 (HDAC8 Produits)

Synonymes: anticorps HD8, anticorps CDLS5, anticorps HDACL1, anticorps MRXS6, anticorps RPD3, anticorps WTS, anticorps 2610007D20Rik, anticorps RGD1562895, anticorps wu:fd19a02, anticorps zgc:66196, anticorps ATHDA8, anticorps HDA8, anticorps HISTONE DEACETYLASE 8, anticorps T27G7.14, anticorps T27G7_14, anticorps histone deacetylase 8, anticorps histone deacetylase 8, anticorps histone deacetylase 8 L homeolog, anticorps CC1G_05302, anticorps hdac8, anticorps HDAC8, anticorps Hdac8, anticorps hdac8.L, anticorps HDA08

Sujet: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by HDAC8 gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 42 kDa

ID gène: 558

NCBI Accession: NP_001159

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process