TWIST2 anticorps (AA 26-30)

N° du produit ABIN871769

Détail du produit anti-TWIST2 anticorps

Antigène: TWIST2 (Twist Homolog 2 (TWIST2))

Épitope: AA 26-30

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TWIST2 est non-conjugé

Application: Western Blotting (WB)

Specificité: The antibody detects endogenous level of total Twist2 protein.

Purification: Affinity purified

Immunogène: Peptide sequence around AA 26-30 (P-K-R-F-G) derived from Human Twist2. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.

Information d'application

Indications d'application: Western blotting 1:100-1:500
Immunohistochemistry  1:100-1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Détails sur TWIST2

Antigène: TWIST2 (Twist Homolog 2 (TWIST2))

Autre désignation: Twist2 (TWIST2 Produits)

Synonymes: anticorps TWIST2, anticorps DERMO1, anticorps FFDD3, anticorps SETLSS, anticorps bHLHa39, anticorps Dermo1, anticorps CDERMO-1, anticorps twist family bHLH transcription factor 2, anticorps twist basic helix-loop-helix transcription factor 2, anticorps TWIST2, anticorps Twist2

Sujet: Binds to the E-box consensus sequence 5'-CANNTG-3' as a heterodimer and inhibits transcriptional activation by MYOD1, MYOG, MEF2A and MEF2C. Also represses expression of proinflammatory cytokines such as TNFA and IL1B. Involved in postnatal glycogen storage and energy metabolism. Inhibits the premature or ectopic differentiation of preosteoblast cells during osteogenesis, possibly by changing the internal signal transduction response of osteoblasts to external growth factors.

ID gène: 117581

NCBI Accession: NP_476527

UniProt: Q8WVJ9

Pathways: Chromatin Binding