PLEKHG6 anticorps (AA 451-550)

N° du produit ABIN873214

Détail du produit anti-PLEKHG6 anticorps

Antigène: PLEKHG6 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6))

Épitope: AA 451-550

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLEKHG6 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human MyoGEF

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur PLEKHG6

Antigène: PLEKHG6 (Pleckstrin Homology Domain Containing, Family G (With RhoGef Domain) Member 6 (PLEKHG6))

Autre désignation: MyoGEF (PLEKHG6 Produits)

Synonymes: anticorps MyoGEF, anticorps BC026778, anticorps Gm155, anticorps pleckstrin homology and RhoGEF domain containing G6, anticorps pleckstrin homology domain containing, family G (with RhoGef domain) member 6, anticorps PLEKHG6, anticorps Plekhg6

Sujet:

Synonyms: Myosin interacting guanine nucleotide exchange factor, PH domain containing family G member 6, Pleckstrin homology domain containing family G with RhoGef domain member 6, Pleckstrin homology domain-containing family G member 6, PLEKHG6_PKHG6_HUMAN

Background: MyoGEF functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.

ID gène: 55200