CNIH2, CNIH3 (AA 25-120) anticorps (FITC)

N° du produit ABIN891494

Détail du produit

Antigène: CNIH2, CNIH3

Épitope: AA 25-120

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: FITC

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Specificité: This antibody detects both CNIH2 and CNIH3 proteins

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CNIH2/CNIH3

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CNIH2, CNIH3

Autre désignation: CNIH2/3

Sujet:

Synonyms: Protein cornichon homolog 2, CNIH2, Cornichon family AMPA receptor auxiliary protein 2, Protein cornichon homolog 3, CNIH3, Cornichon family AMPA receptor auxiliary protein 3

Background: CNIH2 and CNIH3 regulate the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). They promote their targeting to the cell membrane and synapses and modulate their gating properties by regulating their rates of activation, deactivation and desensitization. CNIH2 also blocks CACNG8-mediated resensitization of AMPA receptors.

ID gène: 254263, 149111

UniProt: Q6PI25, Q8TBE1