RBM38 anticorps (AA 51-150) (Alexa Fluor 350)

N° du produit ABIN913173

Détail du produit anti-RBM38 anticorps (Alexa Fluor 350)

Antigène: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Épitope: AA 51-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RBM38 est conjugé à/à la Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human RBM38

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur RBM38

Antigène: RBM38 (RNA Binding Motif Protein 38 (RBM38))

Autre désignation: RBM38 (RBM38 Produits)

Synonymes: anticorps rnpc1, anticorps seb4b, anticorps seb4d, anticorps XSeb4R, anticorps MGC89204, anticorps hsrnaseb, anticorps YF-55, anticorps fi25e12, anticorps wu:fi25e12, anticorps zgc:92336, anticorps xseb4r, anticorps HSRNASEB, anticorps RNPC1, anticorps SEB4B, anticorps SEB4D, anticorps dJ800J21.2, anticorps Rnpc1, anticorps Seb4, anticorps Seb4l, anticorps RNA binding motif protein 38, anticorps RNA binding motif protein 38 L homeolog, anticorps rbm38, anticorps rbm38.L, anticorps RBM38, anticorps Rbm38

Sujet:

Synonyms: SEB4D, CLL associated antigen KW 5, CLL-associated antigen KW-5, HSRNASEB, RBM38, RBM38_HUMAN, RNA binding mot protein 38, RNA binding protein 38, RNA binding region RNP1, RRM containing 1, RNA binding region containing protein 1, RNA-binding mot protein 38, RNA-binding protein 38, RNA-binding region-containing protein 1, RNPC1, SEB4, SEB4B, ssDNA binding protein SEB4, ssDNA-binding protein SEB4.

Background: RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Isoform 1, but not isoform 2, has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Plays a role in myogenic differentiation.

ID gène: 55544

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development