TMEM166 anticorps (AA 51-152) (Alexa Fluor 647)

N° du produit ABIN917969

Détail du produit anti-TMEM166 anticorps (Alexa Fluor 647)

Antigène: TMEM166 (FAM176A) (Family with Sequence Similarity 176, Member A (FAM176A))

Épitope: AA 51-152

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMEM166 est conjugé à/à la Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TMEM166

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur TMEM166

Antigène: TMEM166 (FAM176A) (Family with Sequence Similarity 176, Member A (FAM176A))

Autre désignation: TMEM166 (FAM176A Produits)

Synonymes: anticorps Fam176a, anticorps RGD1559797, anticorps Tmem166, anticorps FAM176A, anticorps TMEM166, anticorps BC014699, anticorps eva-1 homolog A, regulator of programmed cell death, anticorps eva-1 homolog A (C. elegans), anticorps Eva1a, anticorps EVA1A

Sujet:

Synonyms: FLJ13391, TMEM 166, Transmembrane protein 166, EVA1A_HUMAN.

Background: TMEM166, also known as FAM176A (family with sequence similarity 176, member A), is a 152 amino acid protein encoded by a gene mapping to human chromosome 2. The second largest human chromosome, 2 consists of 237 million bases encoding over 1,400 genes and making up approximately 8 % of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstr syndrome is due to mutations in the ALMS1 gene. Interestingly, chromosome 2 contains what appears to be a vestigial second centromere and vestigial telomeres which gives credence to the hypothesis that human chromosome 2 is the result of an ancient fusion of two ancestral chromosomes seen in modern form today in apes.

ID gène: 84141