TIMELESS anticorps (N-Term)

N° du produit ABIN925899

Cet anticorps anti-TIMELESS est un anticorps Lapin Polyclonal détectant TIMELESS dans WB. Adapté pour Humain, Souris, Rat, Chien, Boeuf (Vache), Drosophila melanogaster et Xenopus laevis.

Aperçu rapide pour TIMELESS anticorps (N-Term) (ABIN925899)

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Reactivité: Humain, Souris, Rat, Chien, Boeuf (Vache), Drosophila melanogaster, Xenopus laevis

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMELESS est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TIMELESS anticorps

Épitope: N-Term

Réactivité croisée: Chien, Souris, Rat (Rattus), Boeuf (Vache), Grenouille, Mouche des fruits (Drosophila melanogaster)

Immunogène: TIMELESS antibody was raised in rabbit using the N terminal of TIMELESS as the immunogen

Information d'application

Indications d'application: WB: 2.5 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

TIMELESS Blocking Peptide, (ABIN5616606), is also available for use as a blocking control in assays to test for specificity of this TIMELESS antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur TIMELESS

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Autre désignation: TIMELESS

Sujet: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein. Synonyms: Polyclonal TIMELESS antibody, Anti-TIMELESS antibody, timeless homolog, Drosophila antibody.

Pathways: Protein targeting to Nucleus, Photoperiodism