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IGF1R anticorps (Middle Region)

IGF1R Reactivité: Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Poulet, Porc, Xenopus laevis WB, IHC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN926846
  • Antigène Voir toutes IGF1R Anticorps
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Épitope
    • 26
    • 24
    • 24
    • 14
    • 13
    • 11
    • 10
    • 10
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 193
    • 118
    • 99
    • 16
    • 7
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Humain, Souris, Rat, Poisson zèbre (Danio rerio), Boeuf (Vache), Poulet, Porc, Xenopus laevis
    Hôte
    • 176
    • 31
    • 2
    • 1
    Lapin
    Clonalité
    • 178
    • 32
    Polyclonal
    Conjugué
    • 122
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    Cet anticorp IGF1R est non-conjugé
    Application
    • 127
    • 68
    • 61
    • 56
    • 32
    • 27
    • 17
    • 13
    • 13
    • 10
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
     Réactivité croisée
    Souris, Rat (Rattus), Porc, Boeuf (Vache), Poulet, Poisson zebré (Brachydanio rerio), Grenouille
    Purification
    Purified
    Immunogène
    IGF1 R antibody was raised in rabbit using the middle region of IGF1 as the immunogen
    Top Product
    Discover our top product IGF1R Anticorps primaire
  • Indications d'application
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    Commentaires

    IGF1R Blocking Peptide, catalog no. 33R-2144, is also available for use as a blocking control in assays to test for specificity of this IGF1R antibody

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Concentration
    Lot specific
    Buffer
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    Conseil sur la manipulation
    Avoid repeated freeze/thaw cycles.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • Antigène
    IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))
    Autre désignation
    IGF1R (IGF1R Produits)
    Synonymes
    anticorps CMT2N, anticorps CD221, anticorps IGFIR, anticorps IGFR, anticorps JTK13, anticorps IGFIRC, anticorps IGFR1, anticorps IGF-1R, anticorps IGF1R, anticorps DKFZp469I0618, anticorps igf-1r, anticorps xIGF-1R, anticorps xIGFR, anticorps xigf1r, anticorps A330103N21Rik, anticorps D930020L01, anticorps hyft, anticorps igf-ir, anticorps IGF-IR, anticorps IGF-IRb, anticorps wu:fb03h06, anticorps IGF-IRa, anticorps sb:eu1090, anticorps wu:fi20b10, anticorps alanyl-tRNA synthetase, anticorps insulin like growth factor 1 receptor, anticorps insulin-like growth factor 1 receptor, anticorps insulin-like growth factor 1, anticorps insulin-like growth factor I receptor, anticorps insulin like growth factor 1 receptor S homeolog, anticorps insulin-like growth factor 1b receptor, anticorps insulin-like growth factor 1a receptor, anticorps AARS, anticorps IGF1R, anticorps Igf1r, anticorps igf1r, anticorps Igf1, anticorps LOC780503, anticorps LOC100136427, anticorps igf1r.S, anticorps igf1rb, anticorps igf1ra
    Sujet
    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Synonyms: Polyclonal IGF1R antibody, Anti-IGF1R antibody, insulin-like growth factor 1 receptor antibody, CD221 antibody, IGFIR antibody, JTK13 antibody, MGC142170 antibody, MGC142172 antibody, MGC18216 antibody.
    Pathways
    Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy
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