AIF anticorps (N-Term)

N° du produit ABIN926855

L’anticorps anti-AIF Polyclonal Lapin est utilisé pour la détection de AIF dans des échantillons de Humain, Boeuf (Vache) et Chien. Il a été validé pour WB et IHC.

Aperçu rapide pour AIF anticorps (N-Term) (ABIN926855)

Antigène: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Reactivité: Humain, Boeuf (Vache), Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AIF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-AIF anticorps

Épitope: N-Term

Réactivité croisée: Boeuf (Vache), Chien

Purification: Purified

Immunogène: PDCD8 antibody was raised in rabbit using the N terminal of PDCD8 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

PDCD8 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this PDCD8 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur AIF

Antigène: AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))

Autre désignation: PDCD8

Sujet: AIFM1 (PDCD8) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, AIFM1 induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Synonyms: Polyclonal PDCD8 antibody, Anti-PDCD8 antibodyRP3-438D16.2 antibody, AIF antibody, MGC111425 antibody.

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, L'effet Warburg