IDE anticorps (N-Term)

N° du produit ABIN927297

Cet anticorps anti-IDE Polyclonal Lapin (ABIN927297) détecte spécifiquement IDE dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IDE anticorps (N-Term) (ABIN927297)

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDE est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IDE anticorps

Épitope: N-Term

Purification: Purified

Immunogène: IDE antibody was raised in rabbit using the N terminal of IDE as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

IDE Blocking Peptide, (ABIN936344), is also available for use as a blocking control in assays to test for specificity of this IDE antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur IDE

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Autre désignation: IDE

Sujet: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Synonyms: Polyclonal IDE antibody, Anti-IDE antibody, insulin-degrading enzyme antibody, FLJ35968 antibody, INSULYSIN antibody.

Pathways: SARS-CoV-2 Protein Interactome