IDE anticorps (N-Term)

N° du produit ABIN927297

Détail du produit anti-IDE anticorps

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Épitope: N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IDE est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: IDE antibody was raised in rabbit using the N terminal of IDE as the immunogen

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Commentaires:

IDE Blocking Peptide, catalog no. 33R-10357, is also available for use as a blocking control in assays to test for specificity of this IDE antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur IDE

Antigène: IDE (Insulin-Degrading Enzyme (IDE))

Autre désignation: IDE (IDE Produits)

Synonymes: anticorps zgc:162603, anticorps IDE, anticorps 1300012G03Rik, anticorps 4833415K22Rik, anticorps AA675336, anticorps AI507533, anticorps INSDEGM, anticorps INSULYSIN, anticorps insulin degrading enzyme, anticorps insulin-degrading enzyme, anticorps metallopeptidase, anticorps IDE, anticorps ide, anticorps LOC591315, anticorps CC1G_01115, anticorps Bm1_26615, anticorps PTRG_10875, anticorps SJAG_01430, anticorps EBI_21700, anticorps VDBG_06702, anticorps LOAG_08082, anticorps PGTG_04982, anticorps Tsp_00424, anticorps Ide

Sujet: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Synonyms: Polyclonal IDE antibody, Anti-IDE antibody, insulin-degrading enzyme antibody, FLJ35968 antibody, INSULYSIN antibody.

Pathways: SARS-CoV-2 Protein Interactome