RASGRF1 anticorps (Middle Region)

N° du produit ABIN928864

Cet anticorps Lapin Polyclonal détecte spécifiquement RASGRF1 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RASGRF1 anticorps (Middle Region) (ABIN928864)

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASGRF1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-RASGRF1 anticorps

Épitope: Middle Region

Purification: Purified

Immunogène: RASGRF1 antibody was raised in rabbit using the middle region of RASGRF1 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

RASGRF1 Blocking Peptide, (ABIN5615766), is also available for use as a blocking control in assays to test for specificity of this RASGRF1 antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur RASGRF1

Antigène: RASGRF1 (Ras Protein-Specific Guanine Nucleotide-Releasing Factor 1 (RASGRF1))

Autre désignation: RASGRF1

Sujet: The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. The studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Synonyms: Polyclonal RASGRF1 antibody, Anti-RASGRF1 antibody, Ras protein-specific guanine nucleotide-releasing factor 1 antibody, CDC25 antibody, CDC25L antibody, GNRP antibody, GRF1 antibody, GRF55 antibody, H-GRF55 antibody, PP13187 antibody.

Pathways: Signalisation RTK, Cycle Cellulaire, M Phase