Mre11 anticorps (Middle Region)

N° du produit ABIN928874

L’anticorps anti-Mre11 Polyclonal Lapin est utilisé pour la détection de Mre11 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour Mre11 anticorps (Middle Region) (ABIN928874)

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mre11 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Mre11 anticorps

Épitope: Middle Region

Purification: Purified

Immunogène: MRE11 A antibody was raised in rabbit using the middle region of MRE11 as the immunogen

Information d'application

Indications d'application: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

MRE11A Blocking Peptide, (ABIN5614834), is also available for use as a blocking control in assays to test for specificity of this MRE11A antibody

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Détails sur Mre11

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Autre désignation: MRE11A

Sujet: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog, this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. Synonyms: Polyclonal MRE11A antibody, Anti-MRE11A antibody, MRE11 meiotic recombination 11 homolog A, S. cerevisiae antibody, ATLD antibody, HNGS1 antibody, MRE11 antibody, MRE11B antibody.

Pathways: Réparation de l'ADN