ATF2 anticorps

N° du produit ABIN930912

Cet anticorps anti-ATF2 est un anticorps Souris Monoclonal détectant ATF2 dans IP et DB. Adapté pour Humain.

Aperçu rapide pour ATF2 anticorps (ABIN930912)

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ATF2 est non-conjugé

Application: Immunoprecipitation (IP), Dot Blot (DB)

Clone: ATF25I062

Détail du produit anti-ATF2 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: ATF2 antibody was raised in mouse using recombinant Activating Transcription Factor 2 (Atf2)

Isotype: IgG1

Information d'application

Indications d'application: WB: 0.2-2 µg/mL, IP: 100-500 µg/sample
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: ATF2 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur ATF2

Antigène: ATF2 (Activating Transcription Factor 2 (ATF2))

Autre désignation: ATF2

Sujet: This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined. Synonyms: Monoclonal ATF2 antibody, Anti-ATF2 antibody, Activating transcription factor 2 antibody, HB16 antibody, CREB2 antibody, TREB7 antibody, CRE-BP1 antibody, MGC111558 antibody.

Pathways: Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades