ERCC8 anticorps

N° du produit ABIN931164

Cet anticorps anti-ERCC8 Monoclonal Souris (Clone 235C3a) (ABIN931164) détecte spécifiquement ERCC8 dans DB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour ERCC8 anticorps (ABIN931164)

Antigène: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ERCC8 est non-conjugé

Application: Dot Blot (DB)

Clone: 235C3a

Détail du produit anti-ERCC8 anticorps

Réactivité croisée: Humain

Réactivité croisée (Details): Other species not studied.

Purification: Protein G affinity chromatography

Immunogène: ERCC8 antibody was raised in mouse using recombinant Human Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8

Isotype: IgG1

Information d'application

Indications d'application: Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: Lot specific

Buffer: ERCC8 antibody in PBS (3.0 mM KCl, 1.5 mM KH2 PO4 , 140 mM NaCl, 8.0 mM Na2 HPO4 (pH 7.4)) containing 1 % bovine serum albumin (BSA) and 0.05 % sodium azide (NaN3 ).

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one year. We recommend long term storage at -20 °C.

Détails sur ERCC8

Antigène: ERCC8 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 8 (ERCC8))

Autre désignation: ERCC8

Sujet: This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Synonyms: Monoclonal ERCC8 antibody, Anti-ERCC8 antibody, Excision repair cross complementing rodent repair deficiency complementation group 8 antibody, CSA antibody.

Pathways: Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus