TRAIL anticorps

N° du produit ABIN933806

L’anticorps Souris Monoclonal anti-TRAIL a été validé pour WB, ELISA et Inhibition. Il convient pour détecter TRAIL dans des échantillons de Humain.

Aperçu rapide pour TRAIL anticorps (ABIN933806)

Antigène: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRAIL est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Clone: M912292

Détail du produit anti-TRAIL anticorps

Immunogène: TRAIL antibody was raised in mouse using highly pure recombinant human TRAIL/APO-II as the immunogen.

Isotype: IgG1 kappa

Information d'application

Indications d'application: ELISA: 2-4 µg/mL, Inhibition: 0.3-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Détails sur TRAIL

Antigène: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Autre désignation: TRAIL

Sujet: TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell’s apoptotic machinery. Synonyms: Monoclonal TRAIL antibody, Anti-TRAIL antibody, TNF-related apoptosis-inducing Ligand antibody, TNFSF10 antibody, TL2 antibody.

Poids moléculaire: 20.0 kDa (predicted detection band MW)

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity