TRAIL anticorps
Aperçu rapide pour TRAIL anticorps (ABIN933806)
Antigène
Voir toutes TRAIL (TNFSF10) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Immunogène
- TRAIL antibody was raised in mouse using highly pure recombinant human TRAIL/APO-II as the immunogen.
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Isotype
- IgG1 kappa
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Indications d'application
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ELISA: 2-4 µg/mL, Inhibition: 0.3-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Concentration
- Lot specific
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Buffer
- Lyophilized from PBS.
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Conseil sur la manipulation
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
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Autre désignation
- TRAIL
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Sujet
- TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain”, which activates the cell’s apoptotic machinery. Synonyms: Monoclonal TRAIL antibody, Anti-TRAIL antibody, TNF-related apoptosis-inducing Ligand antibody, TNFSF10 antibody, TL2 antibody.
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Poids moléculaire
- 20.0 kDa (predicted detection band MW)
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Pathways
- Apoptose, Positive Regulation of Endopeptidase Activity
Antigène
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