BMP4 anticorps

N° du produit ABIN934071

Cet anticorps anti-BMP4 est un anticorps Souris Monoclonal détectant BMP4 dans WB, ELISA et Inhibition. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour BMP4 anticorps (ABIN934071)

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp BMP4 est non-conjugé

Application: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Clone: M912262

Détail du produit anti-BMP4 anticorps

Purification: Protein A affinity chromatography

Immunogène: BMP4 antibody was raised in mouse using highly pure recombinant human BMP-4 as the immunogen.

Isotype: IgG2b kappa

Information d'application

Indications d'application: ELISA: 4-8 µg/mL, Inhibition: 0.4-0.6 µg/mL, WB: 0.25-0.5 µg/mL
Optimal conditions should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Références pour anticorps anti-BMP4 (ABIN934071)

Calpe, Correia, Sancho-Serra, Krishnadath: "Comparison of newly developed anti-bone morphogenetic protein 4 llama-derived antibodies with commercially available BMP4 inhibitors." dans: mAbs, Vol. 8, Issue 4, pp. 678-88, (2017) (PubMed).

Détails sur BMP4

Antigène: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Autre désignation: BMP4

Sujet: Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Synonyms: Monoclonal BMP4 antibody, Anti-BMP4 antibody, BMP-4 antibody, Bone Morphogenetic antibody, 4 antibody, BMP-2B antibody, DVR4 antibody.

Poids moléculaire: 31-36 kDa (predicted detection band MW)

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development