ATP6V0B anticorps (Middle Region)

N° du produit ABIN950566

Détail du produit anti-ATP6V0B anticorps

Antigène: ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))

Épitope: AA 111-139, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP6V0B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to ATP6V0B.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 111-139 amino acids from the Central region of human ATP6V0B

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) sodium azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ATP6V0B

Antigène: ATP6V0B (ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B (ATP6V0B))

Autre désignation: ATP6V0B (ATP6V0B Produits)

Synonymes: anticorps ATP6F, anticorps HATPL, anticorps VMA16, anticorps 2310024H13Rik, anticorps Atp6f, anticorps ATPase H+ transporting V0 subunit b, anticorps ATPase, H+ transporting, lysosomal V0 subunit B, anticorps ATPase H+ transporting V0 subunit B, anticorps ATP6V0B, anticorps Atp6v0b

Sujet: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is part of the transmembrane V0 domain and is the human counterpart of yeast VMA16. Two alternatively spliced transcript variants that encode different proteins have been found for this gene.Synonyms: ATP6F, HATPL, V-ATPase 21 kDa proteolipid subunit, V-type proton ATPase 21 kDa proteolipid subunit, Vacuolar proton pump 21 kDa proteolipid subunit

ID gène: 533

NCBI Accession: NP_001034546

Pathways: Transition Metal Ion Homeostasis, Proton Transport