CD247 anticorps (AA 151-164) (FITC)

N° du produit ABIN951240

Détail du produit anti-CD247 anticorps (FITC)

Antigène: CD247 (CD247 Molecule (CD247))

Épitope: AA 151-164

Reactivité: Humain, Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp CD247 est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Specificité: The antibody reacts with CD3 zeta chain (CD247), which is a component of TCR/CD3 complex expressed on T cells.

Réactivité croisée (Details): Species reactivity (tested):Human and Mouse.

Attributs du produit: Synonyms: T3Z, TCRZ, CD3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T-cell receptor T3zeta chain

Immunogène: Synthetic peptide corresponding to amino acids 151-164 of Mouse CD3 zeta

Clone: H146-968

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry: 2 μg/mL (starting point).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.4 with 15 mM Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CD247

Antigène: CD247 (CD247 Molecule (CD247))

Autre désignation: CD247 / CD3Z (CD247 Produits)

Synonymes: anticorps CD3-ZETA, anticorps CD3H, anticorps CD3Q, anticorps CD3Z, anticorps T3Z, anticorps TCRZ, anticorps 4930549J05Rik, anticorps A430104F18Rik, anticorps AW552088, anticorps Cd3, anticorps Cd3-eta, anticorps Cd3-zeta, anticorps Cd3h, anticorps Cd3z, anticorps Cd3zeta, anticorps T3z, anticorps Tcrk, anticorps Tcrz, anticorps LOC100136514, anticorps LOC100136549, anticorps LOC100305023, anticorps CD247, anticorps TCRzeta, anticorps CD247 molecule, anticorps CD247 antigen, anticorps CD3zeta-2, anticorps CD3zeta-1, anticorps Cd247 molecule, anticorps CD247, anticorps Cd247, anticorps cd3z, anticorps cd247

Sujet: CD3 complex is crucial in transducing antigen-recognition signals into the cytopasm of T cells and in regulating the cell surface expression of the TCR complex. T cell activation through the antigen receptor (TCR) involves the cytoplasmic tails of the CD3 subunits CD3 gamma, CD3 delta, CD3 epsilon and CD3 zeta (CD247). These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation.Synonyms: CD3 zeta chain, T-cell receptor T3 zeta chain, T-cell surface glycoprotein CD3 zeta chain, T3Z, TCRZ

ID gène: 12503

UniProt: P24161

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway