CD8B anticorps (Biotin)

N° du produit ABIN951402

Cet anticorps anti-CD8B est un anticorps Rat Monoclonal détectant CD8B dans FACS. Adapté pour Souris.

Aperçu rapide pour CD8B anticorps (Biotin) (ABIN951402)

Antigène: CD8B (CD8b Molecule (CD8B))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD8B est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: CT-CD8b

Détail du produit anti-CD8B anticorps (Biotin)

Specificité: This anti-mouse CD8β Chain monoclonal antibody reacts with the mouse CD8 chain. The CD8 β Chain is also named Ly-3. The CD8 chain associates with the CD8 chain to form the CD8 / heterodimer on MHC class I restricted T-cells (cytotoxic T cells) and most thymocytes1. Since a small subset of T cells (IEL cells) express CD8 / homodimers rather than CD8 / heterodimers, investigators should use an antibody directed against the CD8 chain (CL168B, clone CT-CD8a) to definitively label mouse CD8 cells.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, 0.1 % NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. Should this product contain a precipitate we recommend microcentrifugation before use.

Détails sur CD8B

Antigène: CD8B (CD8b Molecule (CD8B))

Autre désignation: CD8 beta

Sujet: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8B, CD8B1, T-cell surface glycoprotein CD8 beta chain

ID gène: 12526

NCBI Accession: NP_033988

UniProt: P10300

Pathways: TCR Signaling