anticorps CHD1L, anticorps ALC1, anticorps CHDL, anticorps 4432404A22Rik, anticorps Alc1, anticorps Snf2p, anticorps zgc:56084, anticorps chromodomain helicase DNA binding protein 1 like, anticorps chromodomain helicase DNA binding protein 1-like, anticorps CHD1L, anticorps chd1l, anticorps Chd1l
Sujet
In response to DNA strand breaks, chromatin adopts a relaxed structure due to the addition of poly(ADP-ribose) (PAR) to chromatin proteins by PARP enzymes (see PARP1, MIM 173870), and this relaxation facilitates the repair of DNA damage. CHD1L interacts with PAR and has a role in chromatin relaxation following DNA damage (Ahel et al., 2009 [PubMed 19661379]).[supplied by OMIM].Synonyms: ALC1, Amplified in liver cancer protein 1, Chromodomain-helicase-DNA-binding protein 1-like