EIF3K anticorps (C-Term)

N° du produit ABIN952051

Détail du produit anti-EIF3K anticorps

Antigène: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Épitope: AA 175-204, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3K est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to EIF3K.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide between 175-204 amino acids from the C-terminal region of human EIF3K

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS, 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-EIF3K (ABIN952051)

López-González, Schlüter, Aso, Garcia-Esparcia, Ansoleaga, LLorens, Carmona, Moreno, Fuso, Portero-Otin, Pamplona, Pujol, Ferrer: "Neuroinflammatory signals in Alzheimer disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species." dans: Journal of neuropathology and experimental neurology, Vol. 74, Issue 4, pp. 319-44, (2015) (PubMed).

Zhou, Sandercock, Fraser, Ridlova, Stephens, Schenauer, Yokoi-Fong, Barsky, Leary, Hershey, Doudna, Robinson: "Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 47, pp. 18139-44, (2008) (PubMed).

Lin, Chen, Lin, Wang, Inoko, Inagaki, Wu, Chen: "eIF3k regulates apoptosis in epithelial cells by releasing caspase 3 from keratin-containing inclusions." dans: Journal of cell science, Vol. 121, Issue Pt 14, pp. 2382-93, (2008) (PubMed).

Damoc, Fraser, Zhou, Videler, Mayeur, Hershey, Doudna, Robinson, Leary: "Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry." dans: Molecular & cellular proteomics : MCP, Vol. 6, Issue 7, pp. 1135-46, (2007) (PubMed).

Masutani, Sonenberg, Yokoyama, Imataka: "Reconstitution reveals the functional core of mammalian eIF3." dans: The EMBO journal, Vol. 26, Issue 14, pp. 3373-83, (2007) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Schweizer, Bowden, Coulombe, Langbein, Lane, Magin, Maltais, Omary, Parry, Rogers, Wright: "New consensus nomenclature for mammalian keratins." dans: The Journal of cell biology, Vol. 174, Issue 2, pp. 169-74, (2006) (PubMed).

Détails sur EIF3K

Antigène: EIF3K (Eukaryotic Translation Initiation Factor 3 Subunit K (EIF3K))

Autre désignation: EIF3K / EIF3S12 (EIF3K Produits)

Synonymes: anticorps eif3s12, anticorps EIF3S12, anticorps ACYPI000023, anticorps eIF3k, anticorps EIF3-p28, anticorps HSPC029, anticorps M9, anticorps MSTP001, anticorps PLAC-24, anticorps PLAC24, anticorps PRO1474, anticorps PTD001, anticorps 1200009C21Rik, anticorps Eif3s12, anticorps zgc:110726, anticorps eukaryotic translation initiation factor 3 subunit K L homeolog, anticorps eukaryotic translation initiation factor 3 subunit K, anticorps eukaryotic translation initiation factor 3, subunit K, anticorps eukaryotic translation initiation factor 3 subunit k, anticorps Eukaryotic translation initiation factor 3 subunit K, anticorps eif3k.L, anticorps EIF3K, anticorps eif3k, anticorps ANI_1_1610144, anticorps AOR_1_2266174, anticorps Tsp_00068, anticorps Tsp_13184, anticorps Eif3k, anticorps LOC733122, anticorps eif-3.K

Sujet: The 700-kD eukaryotic translation initiation factor-3 (eIF3) is the largest eIF and contains at least 12 subunits, including EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 40S preinitiation complex (Mayeur et al., 2003 [PubMed 14519125]).Synonyms: Eukaryotic translation initiation factor 3 subunit 12, Eukaryotic translation initiation factor 3 subunit K, Muscle-specific gene M9 protein, PLAC-24, eIF-3 p25, eIF-3 p28

Poids moléculaire: 25060 Da

ID gène: 27335

NCBI Accession: NP_037366

Pathways: Ribonucleoprotein Complex Subunit Organization