LFNG anticorps (Middle Region)

N° du produit ABIN953163

Cet anticorps anti-LFNG Polyclonal Lapin (ABIN953163) détecte spécifiquement LFNG dans WB et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour LFNG anticorps (Middle Region) (ABIN953163)

Antigène: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LFNG est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LFNG anticorps

Épitope: AA 93-122, Middle Region

Specificité: This antibody recognizes Human LFNG (Center).

Purification: Protein A column, followed by peptide affinity purification

Immunogène: KLH conjugated synthetic peptide between 93~122 amino acids from the Central region of human LFNG

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS containing 0.09 % (W/V) Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur LFNG

Antigène: LFNG (LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG))

Autre désignation: LFNG

Sujet: LFNG belongs to evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This protein is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150).Synonyms: 3-N-acetylglucosaminyltransferase lunatic fringe, Beta-1, EC=2.4.1.222, LFNG, O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

Poids moléculaire: 41773 Da

ID gène: 3955

NCBI Accession: NP_001035257

Pathways: Signalisation Notch