MOB1A anticorps (N-Term)
-
- Antigène Voir toutes MOB1A (MOBKL1B) Anticorps
- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
-
Épitope
- AA 4-33, N-Term
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp MOB1A est non-conjugé
-
Application
- Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes Human MOBKL1B (N-term).
- Purification
- Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
- Immunogène
- KLH conjugated synthetic peptide between 4-33 amino acids from the N-terminal region of Human MOBKL1B
- Isotype
- Ig Fraction
- Top Product
- Discover our top product MOBKL1B Anticorps primaire
-
-
- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- PBS containing 0.09 % (W/V) Sodium Azide as preservative
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
- Antigène
- MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))
- Autre désignation
- MOBKL1B (MOBKL1B Produits)
- Synonymes
- anticorps mob1, anticorps mob4b, anticorps MOB1A, anticorps MOBK1B, anticorps MOB1, anticorps mats1, anticorps mobk1b, anticorps mobkl1b, anticorps MOBKL1B, anticorps wu:fv69d04, anticorps zgc:56189, anticorps C2orf6, anticorps MATS1, anticorps Mob4B, anticorps 4022402H07Rik, anticorps MOB4B, anticorps Mobk1b, anticorps Mobkl1b, anticorps MOB kinase activator 1A L homeolog, anticorps MOB kinase activator 1A, anticorps MOB kinase activator 1A pseudogene, anticorps mob1a.L, anticorps MOB1A, anticorps mob1a, anticorps LOC712156, anticorps Mob1a
- Sujet
- Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.Synonyms: C2orf6, MOB4B, MOBK1B, Mob1 alpha, Mob1 homolog 1B, Mps one binder kinase activator-like 1B, Protein Mob4B
- Poids moléculaire
- 25080 Da
- ID gène
- 55233
- NCBI Accession
- NP_060691
-