MOB1A anticorps (AA 2-216)

N° du produit ABIN7160116

Détail du produit anti-MOB1A anticorps

Antigène: MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))

Épitope: AA 2-216

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOB1A est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Réactivité croisée: Humain

Purification: >95%, Protein G purified

Immunogène: Recombinant Human MOB kinase activator 1A protein (2-216AA)

Isotype: IgG

Information d'application

Indications d'application: Recommended dilution: WB:1:2000-1:5000, IHC:1:100-1:1000, IF:1:200-1:500, IP1:200-1:2000,

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,-80 °C

Stockage commentaire: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Détails sur MOB1A

Antigène: MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))

Autre désignation: MOB1A (MOBKL1B Produits)

Synonymes: anticorps mob1, anticorps mob4b, anticorps MOB1A, anticorps MOBK1B, anticorps MOB1, anticorps mats1, anticorps mobk1b, anticorps mobkl1b, anticorps MOBKL1B, anticorps wu:fv69d04, anticorps zgc:56189, anticorps C2orf6, anticorps MATS1, anticorps Mob4B, anticorps 4022402H07Rik, anticorps MOB4B, anticorps Mobk1b, anticorps Mobkl1b, anticorps MOB kinase activator 1A L homeolog, anticorps MOB kinase activator 1A, anticorps MOB kinase activator 1A pseudogene, anticorps mob1a.L, anticorps MOB1A, anticorps mob1a, anticorps LOC712156, anticorps Mob1a

Sujet:

Background: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L. Acts cooperatively with STK3/MST2 to activate STK38.

Aliases: B1, Mps One Binder kinase activator like 1B (yeast) antibody, C2orf6 antibody, Chromosome 2 open reading frame 6 antibody, FLJ10788 antibody, FLJ11595 antibody, MATS1 antibody, MOB kinase activator 1A antibody, MOB1 antibody, Mob1 alpha antibody, Mob1 homolog 1B antibody, MOB1 Mps One Binder homolog A antibody, MOB1 Mps One Binder kinase activator like 1B antibody, Mob1A antibody, MOB4B antibody, Mob4B protein antibody, MOBK1B antibody, Mobkl1b antibody, MOL1B_HUMAN antibody, Mps one binder kinase activator like 1B antibody, Mps one binder kinase activator-like 1B antibody, Protein Mob4B antibody

UniProt: Q9H8S9