MOB1A anticorps (N-Term)

N° du produit ABIN656811

Détail du produit anti-MOB1A anticorps

Antigène: MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))

Épitope: AA 5-33, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MOB1A est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Homologie: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogène: This MOBKL1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-33 amino acids from the N-terminal region of human MOBKL1B.

Clone: RB19209

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000. FC: 1:10~50

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: MOBKL1B Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Date de péremption: 6 months

Détails sur MOB1A

Antigène: MOB1A (MOBKL1B) (MOB1, Mps One Binder Kinase Activator-Like 1B (MOBKL1B))

Autre désignation: MOBKL1B (MOBKL1B Produits)

Synonymes: anticorps mob1, anticorps mob4b, anticorps MOB1A, anticorps MOBK1B, anticorps MOB1, anticorps mats1, anticorps mobk1b, anticorps mobkl1b, anticorps MOBKL1B, anticorps wu:fv69d04, anticorps zgc:56189, anticorps C2orf6, anticorps MATS1, anticorps Mob4B, anticorps 4022402H07Rik, anticorps MOB4B, anticorps Mobk1b, anticorps Mobkl1b, anticorps MOB kinase activator 1A L homeolog, anticorps MOB kinase activator 1A, anticorps MOB kinase activator 1A pseudogene, anticorps mob1a.L, anticorps MOB1A, anticorps mob1a, anticorps LOC712156, anticorps Mob1a

Sujet: Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38 and STK38L.

Poids moléculaire: 25080

ID gène: 55233

NCBI Accession: NP_060691

UniProt: Q9H8S9