POU3F1 anticorps (Internal Region)

N° du produit ABIN954257

Détail du produit anti-POU3F1 anticorps

Antigène: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Épitope: Internal Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp POU3F1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Séquence: C-HHALHEDGHE AQLE

Specificité: This antibody recognizes OCT6

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, Cow.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the internal region of the protein sequence according to NP_002690.3. Genename: POU3F1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur POU3F1

Antigène: POU3F1 (POU Class 3 Homeobox 1 (POU3F1))

Autre désignation: POU3F1 / OCT6 (POU3F1 Produits)

Synonymes: anticorps OCT6, anticorps OTF6, anticorps SCIP, anticorps Oct-6, anticorps Oct6, anticorps Otf-6, anticorps Otf6, anticorps Scip, anticorps Test1, anticorps Tst-1, anticorps Tst1, anticorps pou50, anticorps wu:fc09d06, anticorps zp-50, anticorps zp50, anticorps zp50pou, anticorps Testes-1, anticorps Xlnrl-34, anticorps nrl-22, anticorps nrl-34, anticorps nrl34-A, anticorps oct-6, anticorps oct6, anticorps pou3f1, anticorps scip, anticorps pou1-A, anticorps POU class 3 homeobox 1, anticorps POU domain, class 3, transcription factor 1, anticorps POU class 3 homeobox 1 L homeolog, anticorps POU class 3 homeobox 1 S homeolog, anticorps POU3F1, anticorps Pou3f1, anticorps pou3f1, anticorps pou3f1.L, anticorps pou3f1.S

Sujet: POU homeodomain proteins are transcriptional regulators that function in various developmental processes (e.g. cell division, differentiation, specification and survival of specific cell types) and participate in the determination of cell fate. The 45 kDa POU transcription factor Oct-6 (also designated SCIP and Tst-1) is expressed by late embryonic Schwann cells of the peripheral nervous system and is also expressed by nonmyelinating Schwann cells in adults. Oct-6 is strongly upregulated in promyelin cells because it is required for the timely differentiation of promyelin cells into myelinating cells. Oct-6 functions during myelination and is required for the proper downregulation of its own gene when myelination proceeds. c-Myc can act synergistically with the POU domain of Oct-6 to produce myelin disease pathogenesis in the mammalian central nervous system.Synonyms: OTF6, Oct-6, Octamer-binding protein 6, Octamer-binding transcription factor 6, POU domain class 3 transcription factor 1, POU domain transcription factor SCIP, SCIP

ID gène: 5453

NCBI Accession: NP_002690