SDCBP2 anticorps (C-Term)

N° du produit ABIN955045

Détail du produit anti-SDCBP2 anticorps

Antigène: SDCBP2 (Syndecan Binding Protein (Syntenin) 2 (SDCBP2))

Épitope: C-Term

Reactivité: Humain, Rat, Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp SDCBP2 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: C-LLHHTMDHSI PDA

Specificité: This antibody is expected to recognise both human isoforms (NP_056500, NP_536737).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human.

Purification: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogène: Peptide with sequence from the C Terminus of the protein sequence according to NP_056500.3, NP_536737.3. Genename: SDCBP2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur SDCBP2

Antigène: SDCBP2 (Syndecan Binding Protein (Syntenin) 2 (SDCBP2))

Autre désignation: Syntenin-2 / SDCBP2 (SDCBP2 Produits)

Synonymes: anticorps SITAC, anticorps SITAC18, anticorps ST-2, anticorps syndecan binding protein 2, anticorps syndecan binding protein (syntenin) 2, anticorps suppression of tumorigenicity 2, anticorps SDCBP2, anticorps Sdcbp2, anticorps ST2

Sujet: Syntenin 2 binds to the cytoplasmic domains of the syndecans: it contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) C-terminal amino acid sequence of the syndecans. Cells that overexpress the fusion protein show numerous cell surface extensions, suggesting that Syntenin 2 may have an effect on cytoskeleton-membrane organization. Therefore, Syntenin 2 may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors.Synonyms: SITAC18, Syndecan-binding protein 2

ID gène: 27111

NCBI Accession: NP_001186713