TAF2 anticorps (C-Term)
Aperçu rapide pour TAF2 anticorps (C-Term) (ABIN955066)
Antigène
Voir toutes TAF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1159-1188, C-Term
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Specificité
- This antibody reacts to TAF2.
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Réactivité croisée (Details)
- Species reactivity (tested):Human and Mouse.
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Purification
- Affinity chromatography on Protein A
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Immunogène
- KLH conjugated synthetic peptide between 1159~1188 amino acids from the C-terminal region of human TAF2
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Isotype
- Ig Fraction
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- PBS, 0.09 % (W/V) sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TAF2 (TAF2 RNA Polymerase II, TATA Box Binding Protein (TBP)-Associated Factor, 150kDa (TAF2))
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Autre désignation
- TAF2
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Sujet
- Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the larger subunits of TFIID that is stably associated with the TFIID complex. It contributes to interactions at and downstream of the transcription initiation site, interactions that help determine transcription complex response to activators.Synonyms: 150 kDa cofactor of initiator function, CIF150, RNA polymerase II TBP-associated factor subunit B, TAF2B, TAFII-150, TAFII150, TBP-associated factor 150 kDa, Transcription initiation factor TFIID subunit 2
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Poids moléculaire
- 136971 Da
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ID gène
- 6873
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NCBI Accession
- NP_003175
Antigène
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