USP15 anticorps (C-Term)

N° du produit ABIN955486

Détail du produit anti-USP15 anticorps

Antigène: USP15 (Ubiquitin Specific Peptidase 15 (USP15))

Épitope: C-Term

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Chien, Porc

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp USP15 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Séquence: NDIENENCMH TN

Specificité: Recognizes USP15 at C-term.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Dog, Pig, Cow.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography

Immunogène: Peptide with sequence from the C Terminus of the protein sequence according to NP_006304.1. Genename: USP15

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris buffered saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur USP15

Antigène: USP15 (Ubiquitin Specific Peptidase 15 (USP15))

Autre désignation: USP15 (USP15 Produits)

Synonymes: anticorps USP15, anticorps UNP, anticorps UNPH-2, anticorps UNPH4, anticorps 4921514G19Rik, anticorps AI327321, anticorps E430033I05Rik, anticorps Gcap18, anticorps mKIAA0529, anticorps Ubp109, anticorps ubiquitin specific peptidase 15, anticorps universal stress protein UspA, anticorps ubiquitin carboxyl-terminal hydrolase 15, anticorps USP15, anticorps RR_RS05795, anticorps LOC100090554, anticorps usp15, anticorps Usp15

Sujet: Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.Synonyms: Deubiquitinating enzyme 15, KIAA0529, Ubiquitin carboxyl-terminal hydrolase 15, Ubiquitin thioesterase 15, Ubiquitin-specific-processing protease 15, Unph-2, Unph4

ID gène: 9958

NCBI Accession: NP_006304