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GRK2 anticorps

ADRBK1 Reactivité: Humain, Souris, Rat, Singe WB, ELISA, IHC, IF Hôte: Souris Monoclonal 3F8 unconjugated
N° du produit ABIN966226
  • Antigène Voir toutes GRK2 (ADRBK1) Anticorps
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Reactivité
    • 99
    • 78
    • 57
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Singe
    Hôte
    • 93
    • 8
    • 2
    • 2
    Souris
    Clonalité
    • 88
    • 17
    Monoclonal
    Conjugué
    • 59
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp GRK2 est non-conjugé
    Application
    • 57
    • 45
    • 31
    • 17
    • 14
    • 13
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    Purification
    Ascitic fluid
    Immunogène
    Purified recombinant fragment of human GRK2 expressed in E. Coli.
    Clone
    3F8
    Isotype
    IgG1
    Top Product
    Discover our top product ADRBK1 Anticorps primaire
  • Indications d'application
    Western Bloting: 1/500 - 1/2000.
    Immunohistochemistry: 1/200 - 1/1000.
    Immunofluorescence: 1/200 - 1/1000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
  • Chen, Long, Wu, Jiang, Ma: "EGF transregulates opioid receptors through EGFR-mediated GRK2 phosphorylation and activation." dans: Molecular biology of the cell, Vol. 19, Issue 7, pp. 2973-83, (2008) (PubMed).

  • Antigène
    GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
    Autre désignation
    GRK2 (ADRBK1 Produits)
    Synonymes
    anticorps Adrbk-1, anticorps Bark-1, anticorps GRK2, anticorps betaARK1, anticorps BARK1, anticorps BETA-ARK1, anticorps GRK-2, anticorps Grk2, anticorps beta-adrenergic receptor kinase 1, anticorps G protein-coupled receptor kinase 2, anticorps Tsp_00497, anticorps grk2, anticorps Grk2, anticorps GRK2
    Sujet
    The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of betaadrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
    Tissue specificity: Expressed in peripheral blood leukocytes
    Synonyms: GRK2, BARK1, FLJ16718, BETA-ARK1, ADRBK1
    Poids moléculaire
    80kDa
    ID gène
    156
    Pathways
    EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling
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