PDPK1 anticorps (3-phosphoinositide Dependent Protein Kinase-1)

Details for Product anti-PDPK1 Antibody No. ABIN966816, Fournisseur: Connectez-vous pour afficher
Antigène
  • pdpk1
  • MGC82080
  • PDK1
  • PDPK2
  • PRO0461
  • Pdk1
  • ATP5A
  • si:zfos-979f1.3
  • 1210
  • BG02759
  • CG1201
  • CG1210
  • DSTPK61
  • Dmel\\CG1210
  • Dstpk61
  • PDK
  • PDK-1
  • PDK1/Pk61C
  • PK61C
  • Pk61C
  • Pk61C/PDK1
  • dPDK-1
  • dPDK1
  • dSTPK61
  • pk61c
  • 3'-phosphoinositide-dependent protein kinase 1
  • 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1
  • ATPDK1
  • AtPDK1
  • T32M21.110
  • T32M21_110
  • 3-phosphoinositide dependent protein kinase 1
  • 3-phosphoinositide dependent protein kinase 1 L homeolog
  • 3-phosphoinositide dependent protein kinase-1
  • ATP synthase, H+ transporting, mitochondrial Fo complex subunit C2 (subunit 9)
  • 3-phosphoinositide-dependent protein kinase 1
  • pyruvate dehydrogenase kinase, isozyme 1
  • pyruvate dehydrogenase kinase 1
  • Phosphoinositide-dependent kinase 1
  • 3'-phosphoinositide-dependent protein kinase 1
  • PDPK1
  • pdpk1.L
  • pdpk1
  • Pdpk1
  • ATP5G2
  • LOC100380750
  • pdk1
  • PDK1
  • Pdk1
  • pdk-1
Reactivité
Humain, Souris, Rat (Rattus)
464
236
229
21
13
12
11
9
6
5
4
3
2
1
1
1
1
1
1
Hôte
Lapin
385
73
17
Clonalité
Polyclonal
Conjugué
Cet anticorp PDPK1 est non-conjugé
18
17
15
11
11
7
7
7
7
7
7
7
7
7
5
5
4
3
3
3
3
3
3
2
2
1
1
1
1
1
Application
Immunohistochemistry (IHC)
322
171
130
91
65
65
44
35
26
11
10
6
3
2
1
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène The antiserum was produced against synthesized non-phosphopeptide derived from human PDK1 around the phosphorylation site of serine 241(A-N-SP-F-V).
Specificité PDK1 (Ab-241) antibody detects endogenous levels of total PDK1 protein.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Plasmids, Primers & others Plasmids, Primers & others PDPK1 products on genomics-online (e.g. as negative or positive controls)
Autre désignation PDK1 (Ab-241) (PDPK1 Antibody Extrait)
Pathways Signalisation PI3K-Akt, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
Indications d'application WB: 1:500~1:1000
IHC: 1:50~1:100.
Restrictions For Research Use only
Format Liquid
Concentration 100ug/100ul.
Buffer Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock -20 °C
Produit citée dans: Scheid, Parsons, Woodgett: "Phosphoinositide-dependent phosphorylation of PDK1 regulates nuclear translocation." dans: Molecular and cellular biology, Vol. 25, Issue 6, pp. 2347-63, 2005 (PubMed).

Lim, Kikani, Wick, Dong: "Nuclear translocation of 3'-phosphoinositide-dependent protein kinase 1 (PDK-1): a potential regulatory mechanism for PDK-1 function." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 24, pp. 14006-11, 2003 (PubMed).

Sato, Fujita, Tsuruo: "Regulation of kinase activity of 3-phosphoinositide-dependent protein kinase-1 by binding to 14-3-3." dans: The Journal of biological chemistry, Vol. 277, Issue 42, pp. 39360-7, 2002 (PubMed).

Chen, Nystrom, Dong, Li, Song, Liu, Quon: "Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism." dans: Biochemistry, Vol. 40, Issue 39, pp. 11851-9, 2001 (PubMed).

Background publications Beausoleil, Jedrychowski, Schwartz, Elias, Villén, Li, Cohn, Cantley, Gygi: "Large-scale characterization of HeLa cell nuclear phosphoproteins." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 33, pp. 12130-5, 2004 (PubMed).

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