SEK1/MKK4 (Ab-261) antibody detects endogenous levels of total SEK1/MKK4 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogène
The antiserum was produced against synthesized non-phosphopeptide derived from human SEK1/MKK4 around the phosphorylation site of Threonine 261 (A-K-TP-R-D).
MAP2K4
Reactivité: Humain, Souris, Rat
WB, IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC: 1:50-1:100.
Restrictions
For Research Use only
Format
Liquid
Concentration
100ug/100ul.
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Wang, Chen, Liao, Deng, Zhou, Huang, Sun: "Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence." dans: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3389-403, (2002) (PubMed).
Leung, Lassam: "The kinase activation loop is the key to mixed lineage kinase-3 activation via both autophosphorylation and hematopoietic progenitor kinase 1 phosphorylation." dans: The Journal of biological chemistry, Vol. 276, Issue 3, pp. 1961-7, (2001) (PubMed).
Antigène
MAP2K4
(Mitogen-Activated Protein Kinase Kinase 4 (MAP2K4))