VAV1 anticorps

N° du produit ABIN967242

Cité dans 4 publications. Cet anticorps anti-VAV1 Polyclonal Lapin (ABIN967242) détecte spécifiquement VAV1 dans IHC. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour VAV1 anticorps (ABIN967242)

Antigène: VAV1 (Vav 1 Oncogene (VAV1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VAV1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-VAV1 anticorps

Specificité: Vav (Ab-174) antibody detects endogenous levels of total Vav protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: The antiserum was produced against synthesized non-phosphopeptide derived from human Vav around the phosphorylation site of tyrosine 174 (E-I-YP-E-D).

Information d'application

Indications d'application: WB: 1:500~1:1000.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100ug/100ul.

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Références pour anticorps anti-VAV1 (ABIN967242)

Amarasinghe, Rosen: "Acidic region tyrosines provide access points for allosteric activation of the autoinhibited Vav1 Dbl homology domain." dans: Biochemistry, Vol. 44, Issue 46, pp. 15257-68, (2005) (PubMed).

Charvet, Canonigo, Billadeau, Altman: "Membrane localization and function of Vav3 in T cells depend on its association with the adapter SLP-76." dans: The Journal of biological chemistry, Vol. 280, Issue 15, pp. 15289-99, (2005) (PubMed).

Miura-Shimura, Duan, Rao, Reddi, Shimura, Rottapel, Druker, Tsygankov, Band, Band: "Cbl-mediated ubiquitinylation and negative regulation of Vav." dans: The Journal of biological chemistry, Vol. 278, Issue 40, pp. 38495-504, (2003) (PubMed).

Kuhne, Ku, Weiss: "A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation." dans: The Journal of biological chemistry, Vol. 275, Issue 3, pp. 2185-90, (2000) (PubMed).

Détails sur VAV1

Antigène: VAV1 (Vav 1 Oncogene (VAV1))

Autre désignation: Vav

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, CXCR4-mediated Signaling Events, BCR Signaling