Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

MEK2 anticorps (AA 1-110)

MAP2K2 Reactivité: Humain, Souris, Rat, Chien, Poulet, Grenouille WB, IP, IF, IHC (f) Hôte: Souris Monoclonal 96-MEK2 unconjugated
N° du produit ABIN967846
  • Antigène Voir toutes MEK2 (MAP2K2) Anticorps
    MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
    Épitope
    • 19
    • 16
    • 13
    • 11
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-110
    Reactivité
    • 135
    • 81
    • 46
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    Humain, Souris, Rat, Chien, Poulet, Grenouille
    Hôte
    • 110
    • 24
    • 1
    • 1
    Souris
    Clonalité
    • 110
    • 26
    Monoclonal
    Conjugué
    • 72
    • 11
    • 11
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MEK2 est non-conjugé
    Application
    • 110
    • 61
    • 36
    • 22
    • 21
    • 20
    • 19
    • 15
    • 14
    • 10
    • 7
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
     Réactivité croisée
    Souris, Poulet, Chien, Grenouille, Humain
    Attributs du produit
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogène
    Rat MEK2 aa. 1-110
    Clone
    96-MEK2
    Isotype
    IgG2a
    Top Product
    Discover our top product MAP2K2 Anticorps primaire
  • Commentaires

    Related Products: ABIN967389

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Store undiluted at -20° C.
  • Tworkowski, Salghetti, Tansey: "Stable and unstable pools of Myc protein exist in human cells." dans: Oncogene, Vol. 21, Issue 55, pp. 8515-20, (2002) (PubMed).

    Downey, Butler, Tapper, Fialkow, Saltiel, Rubin, Grinstein: "Importance of MEK in neutrophil microbicidal responsiveness." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 1, pp. 434-43, (1998) (PubMed).

    Wu, Harrison, Dent, Lynch, Weber, Sturgill: "Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2." dans: Molecular and cellular biology, Vol. 13, Issue 8, pp. 4539-48, (1993) (PubMed).

    Crews, Alessandrini, Erikson: "The primary structure of MEK, a protein kinase that phosphorylates the ERK gene product." dans: Science (New York, N.Y.), Vol. 258, Issue 5081, pp. 478-80, (1992) (PubMed).

    Hattori, Fukuda, Yamashita, Nakamura, Gotoh, Nishida: "Activation of mitogen-activated protein kinase and its activator by ras in intact cells and in a cell-free system." dans: The Journal of biological chemistry, Vol. 267, Issue 28, pp. 20346-51, (1992) (PubMed).

  • Antigène
    MEK2 (MAP2K2) (Mitogen-Activated Protein Kinase Kinase 2 (MAP2K2))
    Autre désignation
    MEK2 (MAP2K2 Produits)
    Synonymes
    anticorps CFC4, anticorps MAPKK2, anticorps MEK2, anticorps MKK2, anticorps PRKMK2, anticorps AA589381, anticorps MK2, anticorps Prkmk2, anticorps ATMKK2, anticorps F27B13.50, anticorps F27B13_50, anticorps MAP KINASE KINASE 1, anticorps MAP kinase kinase 2, anticorps MK1, anticorps map2k2, anticorps wu:fa56c06, anticorps zgc:123171, anticorps zgc:172250, anticorps mitogen-activated protein kinase kinase 2, anticorps mitogen activated protein kinase kinase 2, anticorps MAP kinase kinase 2, anticorps mitogen-activated protein kinase kinase 2a, anticorps mitogen-activated protein kinase kinase 2b, anticorps MAP2K2, anticorps Map2k2, anticorps MKK2, anticorps map2k2a, anticorps map2k2b
    Sujet
    MEK2 (MAP Kinase Kinase 2 or ERK Kinase), a 46 kDa protein kinase, phosphorylates MAP kinases (ERKs) at tyrosine and threonine residues. This phosphorylation results in activation of the MAP kinases. MEK2 is seven amino acids larger and shares 81% identity with MEK1. In cultured cells, MEK2 is activated by serum. In vitro, v-Raf phosphorylates and activates MEK2. It is thought that all of these activated protein kinases are downstream of the Ras signal transduction pathway and represent an integral part of the Ras mitogenic signal. This antibody is routinely tested by western blot analysis.
    Synonyms: MAP Kinase Kinase 2, ERK Kinase
    Poids moléculaire
    46 kDa
    Pathways
    Signalisation MAPK, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Support technique