PPP1R10 anticorps (AA 605-716)

N° du produit ABIN968349

Détail du produit anti-PPP1R10 anticorps

Antigène: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Épitope: AA 605-716

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPP1R10 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Attributs du produit: 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogène: Rat PNUTS aa. 605-716

Clone: 47-PNUTS

Isotype: IgG1

Information d'application

Commentaires:

Related Products: ABIN967389

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 250 μg/mL

Buffer: Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store undiluted at -20°C.

Références pour anticorps anti-PPP1R10 (ABIN968349)

Allen, Kwon, Nairn, Greengard: "Isolation and characterization of PNUTS, a putative protein phosphatase 1 nuclear targeting subunit." dans: The Journal of biological chemistry, Vol. 273, Issue 7, pp. 4089-95, (1998) (PubMed).

Détails sur PPP1R10

Antigène: PPP1R10 (Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 10 (PPP1R10))

Autre désignation: PNUTS (PPP1R10 Produits)

Synonymes: anticorps CAT53, anticorps FB19, anticorps PNUTS, anticorps PP1R10, anticorps R111, anticorps p99, anticorps Fb19, anticorps Pnuts, anticorps 2610025H06Rik, anticorps Cat53, anticorps D17Ertd808e, anticorps CHUNP6885, anticorps fe15d12, anticorps fk54b08, anticorps ppp1r10l, anticorps wu:fe15d12, anticorps wu:fk54b08, anticorps protein phosphatase 1 regulatory subunit 10, anticorps protein phosphatase 1, regulatory subunit 10, anticorps protein phosphatase 1 regulatory subunit 10 S homeolog, anticorps PPP1R10, anticorps Ppp1r10, anticorps ppp1r10.S, anticorps ppp1r10

Sujet: Many aspects of cellular physiology are influenced by the serine/threonine protein phosphatase1 (PP1). It is a highly conserved eukaryotic protein that reverses the action of protein kinases. PP1 is key to such processes as cell division, neuronal metabolism, and protein synthesis. It consists of a catalytic subunit, with a broad substrate specificity, whose action is directed by its association with a family of regulatory proteins including inhibitor-1, inhibitor-2, and NIPP-1. In response to extracellular stimuli, these proteins interact with PP1 and inhibit its catalytic activity. Other regulatory proteins are referred to as targeting subunits because they direct PP1 to specific subcellular locations and modulate its activity. In the cell nucleus, PP1 has been implicated in a variety of processes. Nuclear PP1 exists in high MW complexes with other proteins including NIPP-1. PNUTS (phosphatase 1 nuclear targeting subunit) is a ubiquitously expressed nuclear protein that forms a stable complex with PP1 and is thought to modulate its catalytic activity. Thus, PNUTS is a specific regulatory protein that directs the nuclear function of PP1.

Poids moléculaire: 110 kDa

Pathways: Protein targeting to Nucleus