ATF2 anticorps (Activating Transcription Factor 2)

Details for Product anti-ATF2 Antibody No. ABIN968968, Fournisseur: Connectez-vous pour afficher
Antigène
  • CRE-BP1
  • CREB2
  • HB16
  • TREB7
  • CG12850
  • CG3749
  • dATF-2
  • DmelCG30420
  • CG30420
  • CHN1
  • Atf-2
  • CRE-BP
  • Creb2
  • D130078H02Rik
  • D18875
  • Tg(Gzma-Klra1)7Wum
  • mXBP
  • atf2-A
  • atf2l
  • activating transcription factor 2
  • Activating transcription factor-2
  • activating transcription factor 2 S homeolog
  • ATF2
  • Atf-2
  • Atf2
  • atf2.S
  • atf2
Reactivité
Humain, Souris
690
421
377
29
21
16
14
11
10
9
5
5
2
2
2
1
1
Hôte
Souris
615
54
19
4
Clonalité (Clone)
Monoclonal ()
Conjugué
Cet anticorp ATF2 est non-conjugé
16
16
15
10
10
9
9
9
9
9
9
9
9
9
8
8
6
3
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
501
328
201
133
126
118
92
27
22
14
12
11
6
3
2
2
1
Options
Fournisseur
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N° du produit (Fournisseur)
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Immunogène Purified recombinant fragment of human ATF2 expressed in E. Coli.
Clone 4F12
Isotype IgG1
Purification Ascites
Plasmids, Primers & others Plasmids, Primers & others ATF2 products on genomics-online (e.g. as negative or positive controls)
Antigène
Autre désignation ATF2 (ATF2 Antibody Extrait)
Sujet This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.
Poids moléculaire 55 kDa
ID gène 1386
HGNC 1386
Pathways Signalisation MAPK, Signalisation RTK, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Indications d'application ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer Ascitic fluid containing 0.03 % sodium azide.
Agent conservateur Sodium azide
Précaution d'utilisation This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock 4 °C,-20 °C
Stockage commentaire 4°C, -20°C for long term storage
Images (Fournisseur)
ELISA image for anti-Activating Transcription Factor 2 (ATF2) antibody (ABIN968968) Figure 1: Red: Control Antigen (100 ng), Purple: Antigen (10ng), Green: Antigen (50 n...
Immunohistochemistry (IHC) image for anti-Activating Transcription Factor 2 (ATF2) antibody (ABIN968968) Figure 2: Immunohistochemical analysis of paraffin-embedded lung cancer (left) and br...
Western Blotting (WB) image for anti-Activating Transcription Factor 2 (ATF2) antibody (ABIN968968) Figure 3: Western blot analysis using ATF2 mouse mAb against NIH/3T3 cell lysate.
Produit citée dans: Chen, Takeuchi, Moroi, Hayashida, Kido, Chen, Tomoeda, Uenotsuchi, Tu, Furue, Urabe: "Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma." dans: Journal of dermatological science, Vol. 51, Issue 3, pp. 210-5, 2008 (PubMed).

Bhoumik, Singha, OConnell, Ronai: "Regulation of TIP60 by ATF2 modulates ATM activation." dans: The Journal of biological chemistry, Vol. 283, Issue 25, pp. 17605-14, 2008 (PubMed).

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